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Randomization was stratified by response to ALIMTA in combination with cisplatin induction therapy (CR or PR versus SD), disease stage (IIIb versus IV), and ECOG PS (0 versus 1)
liposomals
Bundle:2 Boxes
Silencing P65 or EAAT3 increases ROS levels and reduces GSH synthesis, but these changes alone are insufficient to trigger significant cell death due to the robust ferroptosis-resistance mechanisms in cancer cells, including the xCT-GSH-GPX4 system and other protective pathways
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